Embryonic stem cells (ESCs) can form any cell in the body. This also means that they have the potential to form tumors. Human neural stem cells (hNSCs) are a specialized subset of stem cells which can only form cells of the nervous system (neurons, oligodendrocytes, and astrocytes), and are thus safer for use as a…

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1987 B.S., Psychology University of Illinois, Champaign-Urbana 1987 Ph.A., Philosophy University of Illinois, Champaign-Urbana 1993 Ph.D., Psychobiology University of California, Irvine 1993-1994 Post-Doctoral Fellow, IRU in Brain Aging University of California, Irvine 1996-1997 Instructor in Neuroscience Harvard Medical School 1997-2003 Assistant Researcher, Institute for Brain Aging & Dementia University of California, Irvine 2001-2002 Director of…

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Biography Google Scholar Research Description and Approach Selected Publications from PubMed Professor & Vice-Chair for Research (PM&R)Physical Medicine & Rehabilitation/Neurological Surgery Anatomy & Neurobiology Institute for Memory Impairments & Neurological Disorders Sue & Bill Gross Stem Cell Center 2026 Gross Hall cummings@uci.edu Working to understand: How neural stem cells interpret the niche; how transplanted stem cells…

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  Establishment of the Department of Anatomy: Moved to Irvine with California College of Medicine in 1968 The Department of Anatomy has a long history dating back to its association with the California College of Medicine, while that college was based in Los Angeles. However, this historical narrative will begin at the time of the…

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  Academic Management Chair: Christine Gall, Ph.D. (cmgall@uci.edu) Vice Chair: David C. Lyon, Ph.D. (dclyon@uci.edu) Director of Graduate Studies: Brian Cummings, Ph.D. (cummings@uci.edu) Assistant to the Chair: Administrative Services Chief Administrative Officer: Lesley Dowd (ldowd@uci.edu) Academic Affairs HR Analyst: Christine Shortt (cshortt@hs.uci.edu) Contract and Grant Accounting: Douglas Schroettinger (dschroet@hs.uci.edu) Coordinator for Graduate and Medical Education…

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Neuroscience Robertson, R.T., J. Baratta, J. Yu and K.M. Guthrie. A role for neurotrophin 3 in target selection by developing cholinergic axonal projections to cerebral cortex. Neuroscience, 2006, 143, 523-539. Lee, Y.-S., C.Y. Li, V. Caiozzo, R.T. Robertson, J. Yu and V, Lin. Repair of spinal cord transection and its effects on muscle mass and…

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Nguyen H.X., Hooshmand, M.J., Saiwai, H., Maddox, J., Salehi, A., Salazar, D., Uchida, N., Anderson, A.J. (In Press). Systemic neutrophil depletion modulates the migration and fate of transplanted human neural stem cells to rescue functional repair. Journal of Neuroscience. Hooshmand, M.J., Nguyen, H.X. #, Piltti, K.M. #, Benavente, F.#, Hong, S., Flanagan, L., Uchida, N,…

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Name Title Location Phone Zot Email Faculty (Primary Appointees) Calof, Anne Professor 2300 Bio Sci III 4-4616 1275 alcalof@uci.edu Chen, Lulu Assistant Professor 113 Irvine Hall 4-3503 1275 chenly@uci.edu Gall, Christine Professor and Chair 3123 Gillespie NRF 4-8652 4292 cmgall@uci.edu Hunt, Robert Assistant Professor 110 Irvine Hall 4-7079 1280 robert.hunt@uci.edu Igarashi, Kei Assistant Professor 112…

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Chair Christine M. Gall Distinguished Professor and Chair Cellular mechanisms of synaptic plasticity Primary Appointees Anne Calof Professor Systems Biology of Neural Stem Cells Lulu Y. Chen Assistant Professor Synapse Development and Maintenance in Neuropsychiatric Disorders Robert F. Hunt Assistant Professor Epilepsy, Disorders of cortical development Kei M. Igarashi Assistant Professor Sensory perception and memory…

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[Xu lab] Professor Xiangmin Xu has been awarded $3.8 million by the National Institute on Aging to conduct an epigenomic analysis of neural circuits in the brain. By revealing molecular changes that occur during the course of Alzheimer’s disease (AD), the team hopes to identify new therapeutic targets and molecular biomarkers for early detection and…

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