Emeritus Faculty

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Scientist: Jamie Wikenheiser, Ph.D

Dr. Jaime Wikenheiser

Associate Adjunct Professor

Director of Medical Gross Anatomy
Director of Surgical Anatomy
Anatomy & Neurobiology

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Research Focus

Working to understand: medical education, pediatric cardiology, pediatric urology, adult urology

Scientific Focus: primary focus centers on medical and surgical education of medical students.  Research focus centers on pediatric cardiology, the molecular mechanisms of coronary artery anomalies and more recently pediatric and adult urology.


Selected Publications

Spradling K, Khoyilar C, Abedi G, Okhunov, Z, Wikenheiser J, Yoon R, Huang J, Youssef RF, Ghoniem G, Landman J. (2015) Redefining the autonomic nerve distribution of the urinary bladder using three-dimensional image reconstruction. Journal of Urology: [Epub ahead of print]

Lusch A, Leary R, Heidari E, Liss MA, Okhunov Z, Perez-Lanzac De Lorca A, Huang J, Wikenheiser J,Landman J.
Intra and extra-renal autonomic nervous system redefined. Journal of Urology. 2014; 191:1060-1065.

Wikenheiser J, Karunamuni G, Sloter E, Walker MK, Roy D, Wilson DL, Watanabe M.
Altering HIF-1α Through 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Exposure Affects Coronary Vessel Development. Cardiovasc Toxicol. 2013 Jun;13(2):161-7.

Karunamuni G, Yang K, Doughman YQ, Wikenheiser JC, Bader D, Barnett J, Austin A, Parsons-Wingerter P, Watanabe M.
(2010). Expression of lymphatic markers during avian and mouse cardiogenesis Anat Rec (Hoboken) 293: 259-270.

Wikenheiser JC, Wolfram J, Gargesha M, Yang K, Karunamuni G, Wilson DL, Semenza GL, Agani F, Fisher SA, Ward N, Watanabe M. (2009).
Altered hypoxia-inducible factor-1 alpha levels correlate with coronary artery anomalies.   Developmental Dynamics 238: 2688-2700.

Newbern J, Zhong J, Wickramasinghe SR, Li X, Wu Y, Samuels I, Cherosky N, Karlo JC, O’Loughlin B, Wikenheiser JC, Gargesha M, Doughman YQ, Charron J, Ginty DD, Watanabe M, Saitta S, Snider WD, Landreth GE.
(2008). Mouse and human phenotypes indicate a critical conserved role for the ERK2 signaling pathway in neural crest development.  Proceedings of the National Academy of Sciences, USA 105: 17115-17120.

Wikenheiser JC, Doughman Y-Q, Fisher SA, Watanabe M.
(2006). Differential levels of tissue hypoxia in the developing chicken heart.   Developmental Dynamics 235: 115-123.

Barbosky L, Lawrence DK, Karunamuni G, Wikenheiser JC, Doughman YQ, Visconti RP, Burch JB, Watanabe M.(2006). Apoptosis in the developing mouse heart. Developmental Dynamics 235: 2592-2602.

Contact Information








306D Med Surge II
Dep't Anatomy & Neurobiology,
School of Medicine,
University of California,
Irvine, CA 92697-1275

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