Emeritus Faculty

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Scientists: Ivan Soltesz, Ph.D.

Dr. Ivan Soltesz

Adjunct Professor:

Anatomy & Neurobiology


Decorative Icon Soltesz Home Page     Decorative Icon Biography     Decorative Icon Research
Decorative Icon   The Soltesz Lab

Research Focus

Working to understand: traumatic brain injury, post-traumatic epilepsy, fever-induced (Febrile) seizures in childhood, learning and memory deficits

Scientific Focus: functions, development and plasticity of hippocampal interneuronal networks. Physiological basis of hyperexcitability. Mechanisms of selective neuronal vulnerability.


Selected Publications

Armstrong C, Krook-Magnuson E, Oijala M, Soltesz I.
Closed-loop optogenetic intervention in mice. Nat Protoc. 2013 Aug;8(8):1475-93.

Bezaire MJ, Soltesz I.
Quantitative assessment of CA1 local circuits: Knowledge base for interneuron-pyramidal cell connectivity. Hippocampus. Sep;23(9):751-85.

Feldt Muldoon S, Soltesz I, Cossart R.
Spatially clustered neuronal assemblies comprise the microstructure of synchrony in chronically epileptic networks. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3567-72.

Krook-Magnuson, E., Armstrong, C, Oijala, M. and Soltesz, I.
On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy. Nature Communications (2013), 2013 Jan 22;4:1376.

Schneider CJ, Bezaire M, Soltesz I.
Toward a full-scale computational model of the rat dentate gyrus.
Front Neural Circuits. 2012;6:83. doi: 10.3389/fncir.2012.00083. Epub 2012 Nov 16.

Varga C, Golshani P, Soltesz I.
Frequency-invariant temporal ordering of interneuronal discharges during hippocampal oscillations in awake mice. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):E2726-34. doi: 10.1073/PNAS.1210929109. Epub 2012 Sep 10.

Armstrong C, Krook-Magnuson E, Soltesz I.
Neurogliaform and Ivy Cells: A Major Family of nNOS Expressing GABAergic Neurons. Front Neural Circuits. 2012;6:23. Epub 2012 May 16.

Armstrong C, Soltesz I.
Basket cell dichotomy in microcircuit function. J Physiol. 2012 Feb 15;590(Pt 4):683-94. Epub 2011 Dec 23.

Krook-Magnuson E, Varga C, Lee SH, Soltesz I.
New dimensions of interneuronal specialization unmasked by principal cell heterogeneity. Trends Neurosci. 2012 Mar;35(3):175-84. Epub 2011 Nov 24.

Krook-Magnuson E, Luu L, Lee SH, Varga C, Soltesz I.
Ivy and neurogliaform interneurons are a major target of μ-opioid receptor modulation. J Neurosci. 2011 Oct 19;31(42):14861-70.

Case M, Soltesz I.
Computational modeling of epilepsy. Epilepsia. 2011 Oct;52 Suppl 8:12-5. doi: 10.1111/j.1528-1167.2011.03225.

Soltesz I.
The Brain Prize 2011: From Microcircuit Organization to Constellations of Brain Rhythms. Trends Neurosci. 2011 Oct;34(10):501-3. Epub 2011 Sep 13.

Lee SY, Foldy C, Szabadics J, Soltesz I.
Cell-type-specific CCK2 receptor signaling underlies the cholecystokinin-mediated selective excitation of hippocampal parvalbumin-positive fast-spiking basket cells. J Neurosci. 2011 Jul 27;31(30):10993-1002.

Contact Information




The Lab

Hannah Kim,
Postdoctoral Fellow
Esther Krook-Magnuson
Postdoctoral Fellow
Sanghun Lee
Postdoctoral Fellow
Ivan Marchionni,
Postdoctoral Fellow
Mattia Maroso
Postdoctoral Fellow
Gergely Szabo
Postdoctoral Fellow
Marianne Bezaire
Graduate Student
Anh Bui
Graduate Student
Calvin Schneider
Graduate Student

Supporting This Work

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Learn more by contacting Pamela Foster, pamela.foster@uci.edu, or by visiting our Get Involved Page, where you can donate online.