Emeritus Faculty

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Scientist: David C. Lyon, Ph.D

Dr. David Lyon

Associate Professor and Vice-Chair:

Anatomy & Neurobiology
Cognitive Sciences

Decorative Icon Lyon Home Page     Decorative Icon Biography     Decorative Icon Research

Research Focus

Working to understand: organization and function of the visual system to provide a framework for studies on visual disorders.

Scientific Focus: relating fine scale circuitry to visual perception in the mammalian visual cortex and thalamus.

Decorative Icon RECENT PUBLICATIONS ON PUBMED

Selected Publications

Very long-range disynaptic V1 connections through layer 6 pyramidal neurons revealed by transneuronal tracing with rabies virus.
Liu Y, Arreola M, Coleman C, Lyon DC.
Eye and Brain. 2014 6:45-56.

Tracing inputs to inhibitory or excitatory neurons of mouse and cat visual cortex with a targeted rabies virus.
Liu YJ, Ehrengruber MU, Negwer M, Shao HJ, Cetin AH, Lyon DC.
Curr Biol. 2013 Sep 23;23(18):1746-55.

Sharper orientation tuning of the extraclassical suppressive-surround due to a neuron's location in the V1 orientation map emerges late in time.
Liu YJ, Hashemi-Nezhad M, Lyon DC.
Neuroscience. 2013 Jan 15;229:100-17.

Morphological approaches to the anatomical dissection of neuronal circuits.
Lyon DC.
In: Neuromethods (Vol. 67), Neuronal Network Analysis: Concepts and Experimental Approaches, T Fellin and MM Halassa, eds. Springer, New York 2012 pp. 375-389.

Lack of robust LGN label following transneuronal rabies virus injections into macaque area V4.
Lyon DC, Rabideau C.
J Comp Neurol. 2012 520(11):2500-11.

The case for primate V3.
Lyon DC, Connolly JD.
Proc Biol Sci. 2012 Feb 22;279(1729):625-33. Epub 2011 Dec 14. Review.

Orientation tuning of the suppressive extraclassical surround depends on intrinsic organization of V1.
Hashemi-Nezhad M, Lyon DC.
Cerebral Cortex. 2012, Feb;22(2):308-26. Epub 2011 Jun 10.

Dynamics of extraclassical surround modulation in three types of V1 neurons.
Liu YJ, Hashemi-Nezhad M, Lyon DC.
J Neurophysiol. 2011,Mar;105(3):1306-17. Epub 2011 Jan 12.

A disynaptic relay from superior colliculus to dorsal stream visual cortex in macaque monkey.
Lyon DC, Nassi JJ, Callaway EM.
Neuron. 2010, Jan 28;65(2):270-9.

Pulvinar contributions to the dorsal and ventral streams of visual processing in primates.
Kaas JH, Lyon DC.
Brain Res Rev. 2007, Oct;55(2):285-96. Epub 2007 Mar 12. Review.

Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons.
Wickersham IR, Lyon DC, Barnard RJ, Mori T, Finke S, Conzelmann KK, Young JA, Callaway EM.
Neuron. 2007, Mar 1;53(5):639-47.

The parvocellular LGN provides a robust disynaptic input to the visual motion area MT.
Nassi JJ, Lyon DC, Callaway EM.
Neuron. 2006, Apr 20;50(2):319-27.

Contact Information

E-mail:

dclyon@uci.edu

Phone:

949-824-0447

FAX:

949-824-9788

Address:

Dept of Anatomy & Neurobiology,
317B Med Surge II,
University of California, Irvine, CA 92697-1275

The Lab


Yong-Jun Liu, Ph.D.
Assistant Specialist II
Andrzej Foik, Ph.D.
Postdoctoral Fellow
Li (Alex) Zhang, Ph.D.
Postdoctoral Fellow
Georgina Lean
Graduate Student
Leo Scholl
Graduate Student

Supporting This Work

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Join us in becoming a part of scientific history, by supporting the work of this lab.

Learn more by contacting Pamela Foster, pamela.foster@uci.edu, or by visiting our Get Involved Page, where you can donate online.