Anesthesiology & Perioperative Care
Anatomy & Neurobiology
Working to understand: spinal cord injury and repair, stem cell science
Scientific Focus: translational research, special interests in developing new treatments for cauda equine and conus medullaris forms of spinal cord injuries.
Serotonergic 5-HT(1A) receptor agonist (8-OH-DPAT) ameliorates impaired micturition reflexes in a chronic ventral root avulsion model of incomplete cauda equina/conus medullaris injury. Exp Neurol. 2013 Jan;239:210-7. doi: 10.1016/j.expneurol.2012.10.015. Epub 2012 Oct 23.
The longitudinal spinal cord injury: Lessons from intraspinal plexus, cauda equina and medullary conus lesions. Handb Clin Neurol. 2012;109:337-54.
Lu P, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES,
Long-distance growth and connectivity of neural stem cells after severe spinal cord injury. Cell. 2012 Sep 14;150(6):1264-73.
Lu P, Blesch A, Graham L, Wang Y, Samara R, Banos K, Haringer V,
Motor axonal regeneration after partial and complete spinal cord transection.
J Neurosci. 2012 Jun 13;32(24):8208-18.
Modulation of the visceromotor reflex by a lumbosacral ventral root avulsion injury and repair in rats. Am J Physiol Renal Physiol. 2012 Sep;303(5):F641-7.
A lumbosacral ventral root avulsion injury and repair model for studies of neuropathic pain in rats. Methods Mol Biol. 2012;851:185-93.
Wu L, Wu J, Chang HH,
Selective plasticity of primary afferent innervation to the dorsal horn and autonomic nuclei following lumbosacral ventral root avulsion and reimplantation in long term studies. Exp Neurol. 2012 Feb;233(2):758-66. Epub 2011 Dec 8.
Systemic administration of fluorogold for anatomical pre-labeling of autonomic and motor neurons in the rat spinal cord compromises urodynamic recordings in acute but not long-term studies. Neurourol Urodyn. 2012 Jan;31(1):162-7. doi: 10.1002/nau.21184. Epub 2011 Aug 8.
Zai L, Ferrari C, Dice C, Subbaiah S,
Inosine augments the effects of a Nogo receptor blocker and of environmental enrichment to restore skilled forelimb use after stroke. J Neurosci. 2011 Apr 20;31(16):5977-88.
Ichiyama RM, Broman J, Roy RR, Zhong H, Edgerton VR,
Locomotor training maintains normal inhibitory influence on both alpha- and gamma-motoneurons after neonatal spinal cord transection. J Neurosci. 2011 Jan 5;31(1):26-33.
Gillespie Neuroscience Research Facility, # 2121
837 Health Science Road
University of California,
Irvine, California 92697
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